Antibiotics is a great success in the fight against bacterial infections. To understand how this fight is won, the first task is to explain exactly what an antibiotic is and does. The word first appeared in the 1940s and it refers to a substance produced by one bacterium or fungus that prevents the growth of another bacterium. It reflects the old saying, "Fight fire with fire". This refers to the use of fire breaks where you produce a controlled burn of one small area in the path of a larger advancing fire. So when the larger fire arrives, it runs out of fuel and dies. Applying this to medicine, research chemists developed a method of culturing bacteria or fungi that would produce a substance capable of killing or preventing other bacteria from reproducing. Penicillin, for example, is produced from a fungus while streptomycin is derived from the bacterium called Streptomyces. Thus, contrary to popular belief, antibiotics are “natural” in the sense that they are derived from bacteria or fungi occurring in the natural world. They are distinguished from drugs that are entirely artificial. For example, the sulphonamides have an antibacterial effect but are completely synthetic.
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There are features of use antibiotics. Antibiotics are far from harmless, as do most other drugs. Should take antibiotics only when they are prescribed by a doctor (in the annotation to almost all antibiotics, you will find a warning: «dispensed by prescription»).
Why?
Firs, nobody can independently establish the exact diagnosis of his illness, especially when it comes to infectious diseases. Even if the diagnosis is established, only a doctor can determine what kind of antibiotic, in what dosages, and for what duration should use it. And one not unimportant point: before you will be assigned one or another antibiotic, the physician should refer you to a laboratory to determine the sensitivity of your organism to a number of medicines used for treatment. Depending on the reaction to the drugs, he writes a suitable antibiotic for you, namely the one to which your organism has issued the maximum response.
Secondly, self-medication with antibiotics leads to the result, counter-productive: you are still sick, but to the doctor becomes more difficult to determine what it is, because the background of antibiotics the disease can be «wiped off» symptoms.
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With advances in medicinal chemistry, most of today's antibacterials chemically are semisynthetic modifications of various natural compounds. These include, for example, the beta-lactam antibacterials, which include the penicillins (produced by fungi in the genus Penicillium), the cephalosporins, and the carbapenems. Compounds that are still isolated from living organisms are the aminoglycosides, whereas other antibacterials—for example, the sulfonamides, the quinolones, and the oxazolidinones—are produced solely by chemical synthesis. In accordance with this, many antibacterial compounds are classified on the basis of chemical/biosynthetic origin into natural, semisynthetic, and synthetic. Another classification system is based on biological activity; in this classification, antibacterials are divided into two broad groups according to their biological effect on microorganisms: bactericidal agents kill bacteria, and bacteriostatic agents slow down or stall bacterial growth.
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